Greg Archer, an editor for the Santa Cruz Good Times recently published a book about food, Shut Up, Skinny Bitches. In an interview in today’s Good Times he has some advice for writers who are trying to get published:
If you are writing fiction, believe in your story. If you have a great story to tell, tell it and don’t be afraid to tell it. At the end of the day, people want to read good stories. Believe in your story and yourself, and don’t take no for an answer.
I keep hearing the stories of famous writers who were rejected innumerable times and kept on (most recently I heard this was the case for the Bronte sisters). The rejection letters can be hard on the ego and it can be easy to lose faith, but I think Greg’s advice is good. Either you believe in your story and just keep on revising, submitting, and believing, or you give up and put it in a drawer (or on a disc). Getting a book published in today’s market sure isn’t easy.
Sylvia Patience, Author 
Good advice! In a recent article in a writing magazine, several published writers stated that it took about as long to get the book published as it took to write it! Wring ain’t for the weak or easily discouraged.